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Diabetes II

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Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia and abnormal carbohydrate, protein, and fat metabolism. Type 2 Diabetes mellitus occurs due to insulin resistance and insulin deficiency. Resulting from the interaction between genetic, environmental, and behavioral risk factors, type 2 Diabetes Mellitus affects the adults and aging population, with steadily increasing prevalence.

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Diabetes patients are highly vulnerable to microvascular and macrovascular complications leading to premature mortality. Despite specific anti-diabetic therapeutic options, the growing prevalence of the illness warrants discovery of novel anti-hyperglycemic drugs. Coping with hyperglycemia in diabetes mellitus is challenging; however, timely diagnosis and initiation of therapy with lifestyle modifications help in the long-term management of the illness. Moreover, despite the family history of diabetes, adopting a healthy lifestyle can prevent the disease from occurring. 

Type 2 Diabetes Mellitus Symptoms and Signs:  

The patient experiences sudden adulthood onset of illness and remains asymptomatic for a longer duration, and often diabetes is diagnosed secondary to unrelated blood testing. Type 2 diabetes mellitus symptoms of include:

  • Polyphagia-extreme hunger

  • Polydipsia-increased thirst

  • Numbness or tingling sensation in the hands and feet

  • Increased urination at night (nocturia)

  • Sudden weight loss

  • Lethargy and fatigue

  • Hyperglycemia- increase in blood sugar level

  • Blurred vision

  • Frequent infections

  • Unhealing or slow healing wound or sore.

Besides, chronic hyperglycemia in diabetes mellitus results in microvascular complications, such as diabetic neuropathy, diabetic nephropathy, and diabetic retinopathy. Also, macrovascular complications include stroke, hypertension, and atherosclerosis. Having type 2 diabetes without treatment means that high sugar levels in your blood can seriously damage parts of your body, including your eyes, heart and feet.


Treatment for Type 2 Diabetes Mellitus:

Current treatment modalities of type 2 Diabetes Mellitus aim to lower blood sugar levels, prevent associated microvascular and macrovascular complications, and improve patients' quality of life. Chronic treatment with oral antihyperglycemic agents such as Biguanides, Sulfonylureas, Meglitinides, Thiazolidinedione, Alpha-Glucosidase Inhibitors, Dipeptidyl-Peptidase IV Inhibitors, and insulin analogues are the mainstay for controlling the rise in blood sugar.  Moreover, strict adherence to the prescribed anti-diabetic medications, lifestyle, and diet modifications are necessary to manage blood sugar.

An insight into Diabetes 2 Biospecimens we offer:

In view of fueling up global diabetic research, Central BioHub is highly committed to providing access to high-quality diabetes patient samples or Diabetes research specimens. Proclaimed as the largest online marketplace for human biosamples, we cater to every Type 2 diabetes specimen demand from researchers and scientists worldwide. We connect the scientists to the certified biosample suppliers nested in different geographical locations with the most simplified online platform.The type 2 diabetes samples or diabetes 2 patient samples  are explicitly tested for routine laboratory investigations offering matrices such as human serum and plasma ( EDTA, Li-heparin, Citrate plasma) evaluated for hemoglobin A1c (HbA1c), blood glucose levels, glutamic acid decarboxylase autoantibodies (GADA); well-preserved at <-18 °C. To enhance authenticity and add value to the research, different types of diabetes specimens are hyper annotated with clinical information, including medical history, comorbidities, medication history, and patient demographic data like age, gender, body mass index (BMI), race, and ethnicity with the country of sample origin. Central BioHub ensures safer and quicker procurement of research samples through our open access, online marketplace, with complete assistance from our scientific experts. Reach out to us today for high-quality, cost-effective Diabetes 2 samples or other human biospecimens.

Explore advanced search options to order type 2 diabetes samples by clicking Clinical Diagnosis, ICD-10-CM Codes, and Laboratory Parameters.

Type 2 diabetes mellitus is a chronic endocrine disorder characterised by hyperglycemia, i.e., increased blood sugar level. It occurs due to several genetic, environmental, and lifestyle factors contributing to insensitivity towards insulin or insulin resistance. It is one of the oldest illnesses known to humankind.
Type 2 diabetes mellitus is prevalent among adults and older populations, affecting humans regardless of gender. However, persons who are at greater risk of developing disease includes: • Persons with a family history of diabetes among biological relatives like parents and siblings • People who are obese or overweight • People at 45 years old or more • Physically inactive people • People who adopt a sedentary lifestyle
Type I diabetes mellitus is an autoimmune disorder resulting from immune-mediated destruction of pancreatic beta cells. In comparison, type 2 diabetes mellitus develops due to insulin resistance or insufficient insulin production. Type 1 diabetes mellitus is diagnosed in children and young adults; on the other hand, type 2 diabetes mellitus is an adult-onset disease.
Type 2 diabetes mellitus biospecimen includes human serum and plasma samples derived from clinically confirmed diabetes patients and suspected individuals. Human serum and plasma samples are subjected for routine laboratory diabetes investigations, like haemoglobin A1c (HbA1c), blood glucose levels, glutamic acid decarboxylase autoantibodies (GADA) cryogenically stored at <-180C at our partners biobank.
Simple blood sugar test can diagnose type 2 diabetes mellitus. Besides routine diabetes investigations such as fasting blood sugar (FBS), random blood sugar (RBS), and postprandial blood sugar (PPBS), haemoglobin A1c (HbA1c) measuring blood sugar for 2 or 3 months, glutamic acid decarboxylase autoantibodies (GADA), glucose tolerance tests yield confirmation of the disease.