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respiratory tract infections pneumonia

Pneumonia

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Pneumonia (ICD-10 J12-18) is one of the catastrophic acute lower respiratory tract infections resulting in significant morbidity and mortality worldwide. The infection or inflammation of the lung parenchyma is characterized by consolidation caused most often by microbial pathogens.

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Despite significant advances in diagnosis and treatment, mortality associated with pneumonia remains high, especially in the very young, immunosuppressed, and elderly population.Based on the environmental setting of acquiring infection, pneumonia is classified into community-acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), ventilator-associated pneumonia (VAP), and healthcare-associated pneumonia (HACP). Prompt diagnosis and early initiation of evidence-based intensive anti-microbial therapy yield effective pneumonia treatment and management and prevent associated fatalities. However, growing antimicrobial resistance globally necessitates newer research on more potent antibiotic discoveries to tackle future infections and pneumonia contagious risks factors

Etiology of Pneumonia:

A broad spectrum of pathogenic microbes, including bacteria, viruses, and fungi, can cause pneumonia. Common pathogens causing pneumonia include:

  • Bacterial pneumonia: M. pneumoniae, streptococcus pneumoniae, C. pneumoniae, H. influenza, staphylococcus aureus, Legionella species, and moraxella catarrhalis etc.

  • Viral pneumonia: Rhinoviruses, coronaviruses, influenza virus, respiratory syncytial virus (RSV), adenovirus, and parainfluenza.

  • Fungal pneumonia is often rare and mainly seen in immunocompromised AIDS patients, caused by histoplasma capsulatum, blastomyces, cryptococcus neoformans, pneumocystis jiroveci (pneumocystis pneumonia), and coccidioides immitis.

Pneumonia Symptoms and Signs:

Depending upon the causative organism, host defense, and extent of infection progression, pathophysiology of pneumonia, signs and pneumonia symptoms vary from mild to severe illness. Generally, patients with bronchopneumonia experience an abrupt onset of fever, chills, confusion, malaise, dyspnea, productive cough, rust-colored sputum or hemoptysis, and pleuritic chest pain. Additionally, lack of early initiation of antibiotic therapy can lead to life-threatening complications like sepsis, pleural effusion, lung abscess or empyema, and acute respiratory distress (ARD), causing death.


Clinical Diagnosis of Pneumonia:

Accurate clinical diagnosis of pneumonia is crucial for effective management  and pneumonia treatment to refrain infection progression. Besides the pneumonia symptoms, chest radiography, physical examination, blood tests, and procalcitonin level (PCT) test guide the infection's preliminary diagnosis. However, in hospitalized patients, pulse oximetry, complete blood count (CBC), arterial blood gasses analysis, serum electrolytes, C-reactive protein level, and microbiological examination of respiratory fluid guarantee accurate diagnostic specificity and identification of pathogens.

An Insight into Pneumonia Biospecimens We Offer:

Central BioHub, an online marketplace for human biospecimens provides the ultimate solution for the fast procurement of high-quality, safe, and reliable human biospecimens. We leverage our global marketing experience to connect certified international biospecimen suppliers and life science researchers through a most straightforward, open access, and interoperable virtual platform offering a great user experience.

Our meticulous collection of Bacterial Pneumonia samples for research are ethically obtained with strict adherence to all mandatory biosample collection and processing standards. We bring typical pneumonia samples of every person of different ages, gender, and ethnicity. Moreover, biosamples carefully isolated from pregnant women with various parameters (positive and negative, different matrices, matched sets) are also available for purchase.

Every pneumonia patient samples such as human serum, plasma, and whole blood, we offer is critically examined for all routine laboratory investigations of pneumonia, including procalcitonin level test (PCT), C-reactive protein, lactate dehydrogenase (LDH), and are hyper-annotated with relevant clinical data. Ensuring strict compliance with hygienic and safety standards, all viral pneumonia samples and bacterial pneumonia samples are stored at <-18 ° Celsius, devoid of cross-contamination. Our highly devoted scientific experts at Central BioHub are ready to assist you in every step of the biosample purchase process. Order pneumonia infection specimens from Central BioHub.

 Explore advanced search options to find matching pneumonia biological samples by clicking  Clinical Diagnosis, ICD-10-CM Codes, and Laboratory Parameters.

Pneumonia is an acute lower respiratory infection in humans caused by bacteria, viruses, and fungus. It is a pathogenic infection that causes severe inflammation of the lungs, resulting in fluid and pus buildup inside alveoli. Pneumonia affects people of every age group and gender. However, children, the elderly, and patients with other comorbid diseases are more likely to develop severe infections in comparison to adults.
Yes, prompt diagnosis and timely initiation of intensive antimicrobial therapy with the appropriate choice of antibiotics can completely cure pneumonia.
Pneumonia is a highly contagious acute respiratory infection caused by bacteria, viruses, and fungi. It spreads from person to person through inhalation of infected droplets arising from coughing and sneezing, touching the contaminated surface during close contact with pneumonia patients.
Pneumonia biospecimens we offer include human serum, plasma, whole blood samples ethically obtained from pneumonia patients. These are biosamples for research genuinely tested for routine laboratory investigation of pneumonia, such as procalcitonin level test, C-reactive protein, lactate dehydrogenase, and hyper-annotated with relevant clinical data. To gain the utmost research benefit, every human biospecimen is cryogenically stored at our biorepository, devoid of contamination.
Lobar pneumonia is a form of acute pneumonia in which one or more lobes of the lungs are inflamed. The inflammation of the intra-alveolar space results in lung consolidation. It is characterised by sudden onset of fever with chills, cough with blood-stained sputum, and difficulty breathing.