Birds are the primary host of the West Nile virus (WNV), and upon feeding, the virus infects mosquito-vectors, subsequently infecting humans by infected Culex mosquito bites. Therefore, the WNV life cycle often alternates between host birds and mosquito-vectors. However, the transmission of infection is also reported from human to human through laboratory acquisition, blood transfusion, organ transplantation, breastfeeding, and transplacental transmission and is often rare.
The major contributing factor for the widespread disease is replicating mosquito-vectors transmitting the virus in favourable seasons. Therefore, public health initiatives for effective mosquito control and personal protection against mosquito bites are the best way to prevent virus invasion.
West Nile symptoms:
Most individuals infected with the West Nile virus are asymptomatic or exhibit mild symptoms and are self-limiting. However, the symptomatic patients exhibit a sudden onset of headache, malaise, low-grade fever, myalgia, chills, vomiting, fatigue, and rashes. In severe viraemia cases, the infection can prolong and develop into neuroinvasive diseases manifested by encephalitis, meningitis, or acute flaccid paralysis. Besides, Lack of FDA-approved vaccination and definitive antiviral therapy can increase the risk of infection-associated fatalities. Therefore, timely differential diagnosis and early initiation of supportive therapy with close monitoring can reduce the complications.
Dignosis of West nile Virus:
For preliminary diagnosis of West Nile disease, physical examination, endemic area exposure, and patient history are helpful. Confirmatory diagnosis usually rests on serological testing and cerebrospinal fluid (CSF) analysis to detect anti-WNV IgM antibodies by molecular diagnostic tests like ELISA and RT-PCR.
Insight to the West Nile Fever Samples We Offer:
Central BioHub is an ideal pathway to procure trusted human biomaterials through a hundred percent reliable innovative virtual platform. We provide biospecimens derived from suspected and clinically confirmed patients of every age, gender, and ethnicity complying with the mandatory standard declarations ideal for tropical research.
The West Nile virus biospecimens are isolated and stored in the most hygienic laboratory environment operated at optimum conditions to make the samples devoid of contaminations. Central BioHub offers West Nile test samples such as saliva, blood, urine, plasma, and serum samples that are tested for West Nile virus IgG and IgM.
A new outlook to scientific advancements and biomedical and diagnostic research is the long-term goal of Central BioHub, and we strive to contribute the best of our services towards the betterment of science and clinical research on tropical disease and neglected tropical diseases. The group of devoted scientific experts of Central BioHub is our epitome, guaranteeing every West Nile disease biospecimens with perfection and utmost reliability. Customer satisfaction and quality service are our priorities. Reach out to us to procure the most authentic, high-quality, and cost-effective tropical disease samples collected exclusively for Tropical medicine and infectious disease research.