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Cardiovascular Diseases

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The cardiovascular system comprises the heart and blood vessels that convey blood, nutrients, and oxygen to and from every body organ and play a vital role in maintaining body homeostasis. Therefore, cardiovascular diseases (CAD) refer to the vast array of diseases or disorders of multiple etiology affecting the typical structure and function of cardiovascular function due to atherosclerosis and increased risk of embolic occlusion in arteries.

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Today, cardiovascular diseases are one of the most prevalent diseases affecting millions of people worldwide. It is the second-largest reason for global morbidity, disability, and premature mortality. With the worldwide rise in mortality rates, early diagnosis and prevention of disease are given utmost priority in the present decade. Nevertheless, adopting a healthy lifestyle can primarily prevent heart disease symptoms, occurrence and associated disability . 

The common cardiovascular diseases include:

  • Coronary artery diseases: This results from the deprivation of oxygenated blood flow to the myocardium, causing angina pectoris, myocardial infarction (MI), and heart failure.

  • Cerebrovascular diseases (CVD): A sudden stoppage or disrupted blood flow to the brain causes stroke and transient ischaemic attack (TIA).

  • Peripheral arterial disease (PAD): Mainly caused by reduced blood flow to the limbs due to peripheral arteries atherosclerosis eventually causing claudication.

  • Aortic disease: It includes a group of conditions affecting the aorta. Common aortic diseases are abdominal aortic aneurysms (AAA) and thoracic aortic aneurysms.

Risk of Cardiovascular Diseases:

Mounting the risk of developing cardiovascular illness, several factors are involved. High blood pressure or hypertensive cardiovascular disease, alcohol consumption, age more than 50 years, smoking,  tobacco use, hyperlipidemia, stress, diabetes mellitus, inactivity, and obesity are the major risk factors of CVD. Besides, family history and ethnicity can also contribute to the risk of developing the illness. Furthermore, men are more likely to develop the condition than women are demonstrating  more signs of heart problems.

Insight to the cardiovascular disease research samples:

Bridging world-class certified real-time global human biospecimens suppliers and biomedical researchers, Central BioHub is the fastest and most trustworthy online marketplace for human research samples. Fueling international research for novel biomedical research Central BioHub brings you the world's most extensive bioinventory.

Banked with millions of genetically diverse human biosamples at Cardiovacular biobanks, Central BioHub offers you the best quality cardiovascular disease patient samples for research. The samples are obtained from patients clinically diagnosed with myocardial ischemia, myocardial infarction, coronary artery diseases, hypertension, and hyperlipidemia. Our wide array of heart disease samples comprises human blood samples ethically derived from voluntary donors of diverse ethnicity, gender, BMI, and age groups. We offer a curated collection of human serum and plasma samples conscientiously tested for cardiovascular disease biomarkers. Troponin I (TnI), troponin T (TnT), brain natriuretic peptide (BNP), N-terminal prohormone b-type natriuretic peptide (NT-proBNP), myoglobin, creatine kinase-MB (CK-MB), and D-dimer are tested to confirm the disease state.

Enhancing research validity, our specimens are hyper annotated with vital clinical information such as diagnosis, patient medical history, heart disease treatment details, and other potential interfering factors. Subjecting to stringent quality control and safety standards, our biorepository preserves every biosample cryogenically, devoid of degradation and contamination at <-18°C and readily available for purchase. Our scientific customer expert assists you in every step of biospecimen acquisition. Hurry up, reach out to us for more information on cardiovascular disease biospecimens. We are always happy to hear from you.

 

Explore advanced search options to order cardiovascular disease patient samples by clicking clinical diagnosis, ICD-10-CM codes, and laboratory parameters

 

Cardiovascular diseases (CVD) are the cluster of diseases affecting the heart and blood vessels such as arteries, arterioles, and veins, impairing their normal structure and functioning. It includes coronary artery disease, peripheral arterial disease, cerebrovascular diseases, and aortic disease. With rising death tolls every year, CVD is one of the leading causes of mortality and the intensive care unit (ICU) admissions globally.
Signs and symptoms of cardiovascular diseases vary depending on the illness and its severity. Most of the individuals remain asymptomatic during the early course of the disease; however, in later stages of cardiac disease, the patient experiences: • Chest pain, chest tightness, or chest discomfort • Tachycardia or bradycardia • Fatigue • Dizziness • Syncope • Shortness of breath • Pain, numbness on legs and arms • Pain on jaws, neck, throat, or shoulders
Cardiac disease biosensors are the biomarkers released during myocardial infarction or myocardial injury. Suspected patients are tested for troponin I (TnI), troponin T (TnT), brain natriuretic peptide (BNP) and N-terminal prohormone b-type natriuretic peptide (NT-proBNP), myoglobin, creatine kinase-MB (CK-MB), and D-dimer for timely, prompt, cost-effective diagnosis of cardiovascular diseases.
These are human biospecimens for research obtained through customised sampling from cardiac disease patients of every gender, sex, and ethnicity. The human plasma and serum samples assiduously screened for cardiac disease biosensors like troponin-I (TnI), troponin-T (TnT), brain natriuretic peptide (BNP), N-terminal prohormone b-type natriuretic peptide (NT-proBNP), myoglobin, creatine kinase-MB (CK-MB), and D-dimer with ultimate precision and cryogenically preserved at our partners biobanks.
Besides symptoms and family history, many diagnostic tests aid in the accurate diagnosis of cardiovascular diseases. It includes, • Blood test to detect cardiac disease biosensors • Echocardiogram • Electrocardiogram (ECG) • MRI • Chest X-ray