Close contact with the influenza patient and contact with contaminated surfaces remains the other potential sources of disease acquisition. Often influenza occurs as a seasonal outbreak and is endemic, especially during winter hitting millions globally.
The disease incidence, the strength of epidemics, mortality, and morbidity effects of influenza depends explicitly on the community's susceptibility. Effective immunization programs by annual influenza vaccine facilitate prevention and control of the epidemic crisis. However, aiming at disease eradication, the need for continuous innovative research persists for a better understanding of the viral infection biology, genomics, immune response to the infection, and the influenza virus epidemiology.
Etiology of Influenza:
Influenza viruses, an RNA-type virus belonging to the family Orthomyxoviridae, exhibit diverse antigenic characteristics and occur in mainly three forms: A, B, and C. Influenza A Virus and Influenza B Virus re known to cause severe disease outbreaks. On the other hand, influenza virus C is generally responsible for sporadic mild upper respiratory symptoms.
Influenza-Clinical Presentation and Complications:
Infected patients usually experience an abrupt onset of flu symptoms such as high-grade fever, myalgia, headache, malaise, and anorexia, traditionally associated with upper respiratory manifestations such as non-productive cough, sore throat, and nasal discharge. In severe viremia, multiple organs such as the lungs, brain, and heart are affected, resulting in severe complications and death. The intricacies of influenza include pulmonary complications like severe primary influenza, viral pneumonia, and secondary bacterial pneumonia. Besides, It also causes non-pulmonary complications such as myocarditis, pericarditis, Guillain–Barré syndrome, encephalitis, acute liver failure, and Reye syndrome. Therefore, timely diagnosis and early initiation of antiviral therapy can significantly reduce its catastrophic effects.
Clinical Diagnosis of Influenza:
Often flu symptoms is a self-limiting infection that can be confirmed by clinical presentation. However, laboratory confirmation of the disease is done by nucleic acid-based tests such as polymerase chain reaction (PCR) or rapid diagnosis kits or rarely virus isolation by culture methods.
Furthermore, rapid diagnosis influenza tests detect viral antigens in the Patient’s respiratory secretions and aids in prompt screening of the infected persons. In comparison, RT-PCR is a molecular test employed to distinguish between the types and sub-types of influenza virus that helps in achieving more specificity and sensitivity in diagnosis.
An Insight into Flu samples or Influenza Biospecimens We Offer:
Accelerating continuous innovative influenza research, Central BioHub offers highly annotated human influenza test samples collected from genuine donors of all ages, gender, and ethnicities suspected or clinically confirmed with influenza. Our inventory comprises highly reliable flu samples such as human serum, plasma, and respiratory secretions (influenza swab test samples) stored at <-18°C at our partner’s biobank. Every influenza sample is accurately tested in certified laboratories for anti-influenza-A IgG and anti-influenza-B IgG to yield disease confirmation. Besides, Central BioHub also provides a larger collection of influenza virus samples exclusive for R&D.
We facilitate top-tier research by providing a seamless experience to order influenza samples online. Our comprehensive online flu sample inventory features a robust selection of influenza research samples, including both Influenza A and B specimen supply online. We understand the critical nature of timely and accurate data, which is why we ensure fast shipping for flu samples coupled with reliable influenza specimen delivery.
Explore advanced search options to find Influenza biospecimens by clicking Clinical Diagnosis, ICD-10-CM Codes, and Laboratory Parameters.