The disease incidence, the strength of epidemics, mortality, and morbidity effects of influenza depends explicitly on the community's susceptibility. Effective immunization programs by annual influenza vaccine facilitate prevention and control of the epidemic crisis. However, aiming at disease eradication, the need for continuous innovative research persists for a better understanding of the viral infection biology, genomics, immune response to the infection, and the influenza virus epidemiology.
Etiology of Influenza:
Influenza viruses, an RNA-type virus belonging to the family Orthomyxoviridae, exhibit diverse antigenic characteristics and occur in mainly three forms: A, B, and C. Influenza A Virus and Influenza B Virus re known to cause severe disease outbreaks. On the other hand, influenza virus C is generally responsible for sporadic mild upper respiratory symptoms.
Influenza-Clinical Presentation and Complications:
Infected patients usually experience an abrupt onset of flu symptoms such as high-grade fever, myalgia, headache, malaise, and anorexia, traditionally associated with upper respiratory manifestations such as non-productive cough, sore throat, and nasal discharge. In severe viremia, multiple organs such as the lungs, brain, and heart are affected, resulting in severe complications and death. The intricacies of influenza include pulmonary complications like severe primary influenza, viral pneumonia, and secondary bacterial pneumonia. Besides, It also causes non-pulmonary complications such as myocarditis, pericarditis, Guillain–Barré syndrome, encephalitis, acute liver failure, and Reye syndrome. Therefore, timely diagnosis and early initiation of antiviral therapy can significantly reduce its catastrophic effects.
Clinical Diagnosis of Influenza:
Often flu symptoms is a self-limiting infection that can be confirmed by clinical presentation. However, laboratory confirmation of the disease is done by nucleic acid-based tests such as polymerase chain reaction (PCR) or rapid diagnosis kits or rarely virus isolation by culture methods.
Furthermore, rapid diagnosis influenza tests detect viral antigens in the Patient’s respiratory secretions and aids in prompt screening of the infected persons. In comparison, RT-PCR is a molecular test employed to distinguish between the types and sub-types of influenza virus that helps in achieving more specificity and sensitivity in diagnosis.
An Insight into Flu samples or Influenza Biospecimens We Offer:
Accelerating continuous innovative influenza research, Central BioHub offers highly annotated human influenza test samples collected from genuine donors of all ages, gender, and ethnicities suspected or clinically confirmed with influenza. Our inventory comprises highly reliable flu samples such as human serum, plasma, and respiratory secretions (influenza swab test samples) stored at <-18°C at our partner’s biobank . Every influenza samples are accurately tested in certified laboratories for anti-influenza-A IgG and anti-influenza-B IgG to yield disease confirmation. Besides, Central BioHub alos provides larger collection of influenza virus samples exclusive for R&D.
Central BioHub commits to fueling research for developing more efficient next-generation universal vaccination, specific anti-influenza therapy, and innovative diagnostic modalities to prevent future disease outbreaks. Connecting global researchers and scientists to the worldwide biospecimen suppliers, Central BioHub refines the process of human biospecimen procurement. Our innovative online platform enables the selection of the suitable high-quality Influenza research samples that you are searching for in a simplified format. In addition, Central BioHub promises you the fast, reliable, worldwide delivery of ordered biospecimens by ensuring complete assistance to your procurement process. Hurry up! Contact us today for more information on influenza A and B samples and other clinical research sample.