panels diabetes i and ii

Diabetes I And II

Diabetes mellitus is a group of chronic metabolic disorders characterized by elevated blood glucose levels resulting from defects in insulin production, action, or both. It is one of the oldest metabolic disorders ever known to humankind with multiple aetiology. Type 1 diabetes mellitus mainly develops due to autoimmune-mediated destruction of pancreatic beta cells with the production of autoantibodies like islet cell antibodies and insulin antibodies. On the other hand, Type 2 Diabetes mellitus occurs due to insulin resistance and insulin deficiency. Also, causes of diabetes are many. Despite advanced anti-diabetic therapeutic options, the growing prevalence of the illness warrants discovery of novel anti-hyperglycemic drugs. Also, explore advanced search options by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

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Insights to Diabetes samples we offer:

Fostering global research on diabetes, Central BioHub provides trustworthy premium quality, clinically graded human biospecimens of type 1 and type 2 diabetes mellitus, cryogenically stored at our partner's biobank. The research samples include human serum and plasma samples obtained from various consented donors, clinically suspected or confirmed with type 1 and type 2 diabetes mellitus symptoms. Moreover, the diabetes mellitus samples we provide are well-annotated with patient’s; medical information, including medication history and demographic data such as age, gender, ethnicity, and country of sample origin. Central BioHub ensures safer and quicker procurement of research samples through our open access, online marketplace, with complete assistance from our scientific experts. Reach out to us today for high-quality, cost-effective human biospecimens.

Type-2 diabetes mellitus is a chronic endocrine disorder characterised by hyperglycemia, i.e., increased blood sugar level. It occurs due to several genetic, environmental, and lifestyle factors contributing to insensitivity towards insulin or insulin resistance. It is one of the oldest illnesses known to humankind.
Type-1 diabetes mellitus, also known as insulin-dependent diabetes mellitus (IDDM), is a metabolic disorder characterised by increased blood glucose levels. It is caused by a mechanism called autoimmunity, where the bodys immune system destroys pancreatic beta cells. Pancreatic beta cells are responsible for producing insulin to regulate blood glucose. Therefore, its destruction results in an imbalance between insulin demand and production, eventually causing hyperglycemia. Although illness onset can be at any age, children and young adults are majorly struck with type-1 diabetes. Therefore, it is known as juvenile diabetes.
The general symptoms of diabetes mellitus include: • Extreme hunger • Increased thirst • Frequent urination • Sudden unintended weight loss • Unhealing or slow healing wound or sore • Lethargy and weakness • Increase in blood sugar level • Irritability and mood swings • Blurred vision
Type-1 diabetes mellitus biospecimens include human serum and plasma samples derived from clinically confirmed patients and suspected individuals with diabetes mellitus. These biosamples are subjected to diabetic biomarker testing, such as autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA), and are stored at <-180 C.
Type-2 diabetes mellitus biospecimen includes human serum and plasma samples derived from clinically confirmed diabetes patients and suspected individuals. Human serum and plasma samples are subjected for routine laboratory diabetes investigations, like haemoglobin A1c (HbA1c), blood glucose levels, glutamic acid decarboxylase autoantibodies (GADA) and are cryogenically stored at <-180C at our partners biobank.