Continuing as one of the world’s contagious deadliest lung infections, tuberculosis is one of the significant public concerns for many decades. Every year, severe health problems are reported due to tuberculosis in low and middle-income countries. Being prevalent in the regions of challenging socio-economic conditions such as crowded human settlements, malnutrition, poverty, and unhygienic conditions, tuberculosis is known as the "disease of poverty". Despite the success rate of bcg vaccine, the emergence of multidrug-resistant tuberculosis (MDR TB) has made it more challenging to treat and to abate the disease incidence.
What are the signs and symptoms of tuberculosis?
Tuberculosis is gradual in onset and is manifested by generalized weakness, weight loss, fever, drenching night sweat, chest pain, persistent productive cough, and frank hemoptysis. Depending upon the strength of the host's immune system, tuberculosis is divided into two:
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Active Tuberculosis: It is the most common form of active lung infection by mycobacterium tuberculosis. The pathogenic bacteria multiply rapidly and invade different organs of the human body and are highly contagious in nature. Patients with active tuberculosis transmit the infection to others through close contact, or infected droplets coughed or sneezed into the air.
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Miliary Tuberculosis: It is a rare form of active tuberculosis with pathogenic bacteria in the bloodstream affecting multiple organs.
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Latent Tuberculosis: Patients with latent tuberculosis are infected with mycobacterium tuberculosis but remain asymptomatic with no active TB. However, the risk of developing an active infection is high in further walks of life.
Clinical Diagnosis of Tuberculosis:
Besides evaluating complete medical history, chest X-ray, and physical examination, active tuberculosis infection can be precisely diagnosed by laboratory testings like the Mantoux tuberculin test (TST) and sputum smear test. TST is the blood test to measure the immune response to mycobacterium tuberculosis, performed by injecting a fluid called tuberculin into the lower region of the arm to inspect the reaction. Besides, microbiological examination of the patient's sputum for acid-fast-bacilli (AFB) followed by 24 hours culture of a positive AFB sample enhances the specificity of the diagnostic test. Additionally, a drug resistance test should be conducted to decide appropriate infection-specific drug choices to optimize infection, especially in MDR tuberculosis.
An Insight into Tuberculosis Samples for Research:
Central BioHub is the most reliable global market leader for providing biospecimens for clinical research. We cater research sample needs of devoted researchers and scientists worldwide. We offer a wide array of tuberculosis samples for invitro-research. Tuberculosis biospecimens are collected from multiple nationalities after undergoing routine tuberculosis diagnostic tests and anti-tuberculosis antibody testing to detect anti-mycobacterium tuberculosis IgG at internationally certified laboratories. Our tuberculosis patient samples include seropositive, seronegative, and suspected blood samples of genuine donors with pulmonary tuberculosis, of every age, sex, and ethnicity. Our biobanks store tuberculosis research samples cryogenically preserved at <-18°C devoid of contamination in the best condition, readily available for purchase.
Central BioHub offers a superior customer experience to every client. Prioritizing fair trade practices, customers can refer to our website for a complete description of our biosample inventory. We are highly motivated scientists passionately working to globally accelerate novel medical, pharmaceutical, diagnostic, and biotech research aiming at tuberculosis prevention. Our scientific experts at Central BioHub provide individualized customer-centric comprehensive assistance to the entire procurement process and promptly address every query. Hurry up, acquire your tuberculosis biomarker samples from Central BioHub, the largest global biosample provider.
Explore advanced search options to order tuberculosis samples for research by clicking on clinical diagnosis, ICD-10-CM codes, and laboratory parameters.