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Tuberculosis

Tuberculosis or TB is a highly contagious airborne single microbial infection affecting the worldwide human population caused by mycobacterium tuberculosis. Millions of people are affected by tuberculosis every year and the leading cause of human mortality worldwide. The pathogenic infection is transmitted through the inhalation of infective droplets nuclei released into the air during coughing and sneezing. Explore advanced search options to order tuberculosis samples for research by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

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Continuing as one of the world’s contagious deadliest lung infections, tuberculosis is one of the significant public concerns for many decades. Every year, severe health problems are reported due to tuberculosis in low and middle-income countries. Being prevalent in the regions of challenging socio-economic conditions such as crowded human settlements, malnutrition, poverty, and unhygienic conditions, tuberculosis is known as the "disease of poverty". Despie the success rate of bcg vaccine, the emergence of multidrug-resistant tuberculosis (MDR TB) has made it more challenging to treat and to abate the disease incidence.


What are the signs and symptoms of tuberculosis?

Tuberculosis is gradual in onset and is manifested by generalised weakness, weight loss, fever, drenching night sweat, chest pain, persistent productive cough, and frank hemoptysis. Depending upon the strength of the host's immune system, tuberculosis is divided into two:

  • Active Tuberculosis: It is the most common form of active lung infection by mycobacterium tuberculosis. The pathogenic bacteria multiply rapidly and invade different organs of the human body and are highly contagious in nature. Patients with active tuberculosis transmit the infection to others through close contact, or infected droplets coughed or sneezed into the air.
  • Miliary Tuberculosis: It is a rare form of active tuberculosis with pathogenic bacteria in the bloodstream affecting multiple organs.
  • Latent Tuberculosis: Patients with latent tuberculosis are infected with mycobacterium tuberculosis but remain asymptomatic with no active TB. However, the risk of developing an active infection is high in further walks of life.

 

Clinical Diagnosis of Tuberculosis:

Besides evaluating complete medical history, chest X-ray, and physical examination, active tuberculosis infection can be precisely diagnosed by laboratory testings like the Mantoux tuberculin test (TST) and sputum smear test. TST is the blood test to measure the immune response to mycobacterium tuberculosis, performed by injecting a fluid called tuberculin into the lower region of the arm to inspect the reaction. Besides, microbiological examination of the patient's sputum for acid-fast-bacilli (AFB) followed by 24 hours culture of a positive AFB sample enhances the specificity of the diagnostic test. Additionally, a drug resistance test should be conducted to decide appropriate infection-specific drug choices to optimize infection, especially in MDR tuberculosis.   


An Insight into Tuberculosis Samples for Research:

Central BioHub is the most reliable global market leader for providing biospecimens for clinical research. We cater research sample needs of devoted researchers and scientists worldwide. We offer a wide array of tuberculosis samples for invitro-research. Tuberculosis biospecimens are  collected from multiple nationalities after subjecting to routine tuberculosis diagnostic tests and anti-tuberculosis antibody testing to detect anti-mycobacterium tuberculosis IgG at internationally certifies laboratories. Our tuberculosis patient samples include seropositive, seronegative, and suspected blood samples of genuine donors with pulmonary tuberculosis, mdr tb of every age, sex, and ethnicity. Our biorepository stores tuberculosis research samples cryogenically preserved at <-18°C devoid of contamination in the best condition, readily available for purchase.


Central BioHub offers a superior customer experience to every client. Prioritizing fair trade practices, customers can refer to our website for a complete description of our biosample inventory. We are highly motivated scientists passionately working to globally accelerate novel medical, pharmaceutical, diagnostic, and biotech research aiming tuberculosis prevention. Our scientific experts at Central BioHub provide individualized customer-centric comprehensive assistance to the entire procurement process and promptly address every query. Hurry up, acquire your tuberculosis biomarker samples from Central BioHub, the largest global biosample provider.

Tuberculosis (TB) is an airborne bacterial infection caused by mycobacterium tuberculosis, also called TB bacteria. It is transmitted through the contact or inhalation of infected droplets released into the air during coughing and sneezing. It is the leading single microbial infection affecting the world population regardless of age and gender.
Signs and symptoms of tuberculosis include: • Fever • Persistent cough with sputum for more than three months, coughing up blood • Drenching night sweat • Sudden weight loss • Fatigue • Loss of appetite
Patients with multi-drug resistant TB will not be responding to the first-line antitubercular drugs like isoniazid and rifampicin or both. It is caused by the tuberculosis bacteria showing resistance to these potent antitubercular drugs or developed resistance during treatment.
Yes, Bacillus Calmette-Guerin (BCG) vaccine protects actively against tuberculosis. It is a single-dose attenuated live vaccine administered to infants intradermally on the upper arm in high-risk countries. Moreover, BCG has proved the most significant effect in preventing military TB and TB meningitis.
Tuberculosis can be treated effectively by antitubercular medications. Strict adherence to the isoniazid, rifampicin, pyrazinamide, ethambutol is necessary to achieve a non-infectious state.