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What is Grave’s disease?

Grave's disease is a chronic autoimmune Disease affecting the thyroid gland resulting in immune hyperthyroidism. The overactive thyroid gland secretes an excess amount of thyroid hormones that accelerate body metabolism leading to sudden unintended weight loss. Grave's disease affects people of every age. It is one of the most common autoimmune diseases prevalent worldwide, predominantly seen in women rather than men. In Grave's disease, the body’s immune system mistakenly produces autoantibodies and attacks the thyroid gland and pituitary gland, causing an overproduction of thyroid hormones. However, the exact reason behind this immune system malfunctioning is unclear. It is the leading cause for thyroid eye disease.

How to diagnose Grave's Disease?

A thorough clinical evaluation of Graves disease symptoms and signs, patient and family history guides physicians in the preliminary diagnosis of Grave's Hyperthyroidism. Besides, Graves disease diagnosis focuses on thyroid function tests and blood tests are carried out to confirm the diagnosis of the illness. Blood tests screen levels of thyroid-stimulating hormone (TSH) and thyroid hormones. Specific antibody testing detects antibodies like anti-thyroid peroxidase (anti-TPO) and thyrotropin receptor antibodies responsible for causing Grave's disease. Prompt diagnosis and early initiation of Graves disease treatment can significantly improve the symptoms of the disease.

Central BioHub Offers Grave's Disease Biospecimens Online

With the most prominent research biospecimen inventory, Central BioHub has a proven record of service history of meeting the thyroid research specimens needs of biomedical researchers worldwide. We are dedicated to offering annotated and quality-checked Grave's disease samples obtained ethically from diverse patients through customized sampling procedures. Maintaining strict anonymity, we provide thyroid disease biospecimens descriptions such as relevant clinical information, medication details, and donor demographics like age, gender, ethnicity, body mass index, and country of sample origin. All autoimmune thyroiditis samples are incisively measured for autoantibodies like antithyroid peroxidase (anti-TPO) and thyrotropin receptor antibodies.

Central BioHub eases the process of human biospecimen procurement by connecting biomedical researchers to worldwide human biobank. Our innovative online platform enables the selection of the suitable high-quality research samples that you are looking for. Central BioHub offers high quality, clinical grade bio-specimens, cryogenically preserved sera (serum), plasma, and peripheral blood mononuclear cells (PBMC) biofluid samples from Graves' Disease patients exclusively for research and development. Our scientific customer experts provide completely customized customer-centric assistance to your whole procurement process. Contact us now for more information on clinical research samples.  Also, explore advanced search options to order autoimmune thyroid samples by clicking clinical diagnosis, ICD-10-CM codes, and laboratory parameters.

Graves disease is a long-term autoimmune condition that affects the thyroid gland and is characterized by hyperthyroidism, which causes the body to produce more thyroid hormones than normal and speeds up metabolism. Women are more likely to be affected than males, and it primarily affects persons in their middle years.
Any person, regardless of age, can get Graves disease. The likelihood of contracting the disease can, however, be influenced by a variety of risk factors, such as: Family history of Graves disease Sex: Women are more likely to develop Graves disease than men Presence of other autoimmune disorders like rheumatoid arthritis, type-1 diabetes mellitus, and lupus. Age: onset of illness is usually before 40 years Pregnancy Smoking
Graves disease is a chronic autoimmune endocrine condition that necessitates for long-term radioactive iodine therapy as well as antithyroid drugs like methimazole and propylthiouracil to reduce abnormal overproduction of thyroid hormones. Depending on the diseases symptoms, some patients need thyroid surgery (thyroidectomy).
Graves disease biospecimens are human samples for research ethically obtained from Graves disease patients. It includes serum and plasma samples critically measured for Graves disease antibodies such as antithyroid peroxidase and thyrotropin receptor antibodies and stored at our biobank for research use.