Sepsis is a life-threatening condition caused by an overwhelming response of the immune system to an infection of the blood stream. This infection can be triggered by bacteria, viruses, fungi or parasites. Central BioHub offers blood samples of sepsis patients that were tested for an infection with E. coli, Pseudomonas, Streptococcus and Staphylococcus.

What is the treatment for Sepsis?

In order to control the infection, broad-spectrum antibiotics are administered as early as possible during the course of sepsis. Afterwards, the infection needs to be localized and treated appropriately. Another crucial aspect of treating sepsis is to stabilize the patient´s vital parameters and support affected organs to avoid organ failures.

What are the challenges of treating Sepsis?

As an infection will spread quickly throughout the body, early recognition and precise diagnosis are the key elements of a successful treatment. Besides the difficulties of stabilizing the patient body, antibiotic resistance is a major threat for patients with sepsis. Central BioHub is therefore eager to support researchers in discovering new drug targets by supplying them with human sepsis samples to conduct biomedical studies.

How can Sepsis be prevented?

The key of preventing sepsis is to avoid infections in the first place by good hygiene practices. On top of that, certain vaccinations and responsible antibiotic stewardship to avoid antibiotic resistance can help to minimize the risk of developing sepsis.