Sepsis is a life-threatening condition caused by an overwhelming response of the immune system to an infection of the blood stream. This infection can be triggered by bacteria, viruses, fungi or parasites. Central BioHub offers blood samples of sepsis patients that were tested for an infection with E. coli, Pseudomonas, Streptococcus and Staphylococcus.

What is the treatment for Sepsis?

In order to control the infection, broad-spectrum antibiotics are administered as early as possible during the course of sepsis. Afterwards, the infection needs to be localized and treated appropriately. Another crucial aspect of treating sepsis is to stabilize the patient´s vital parameters and support affected organs to avoid organ failures.

What are the challenges of treating Sepsis?

As an infection will spread quickly throughout the body, early recognition and precise diagnosis are the key elements of a successful treatment. Besides the difficulties of stabilizing the patient body, antibiotic resistance is a major threat for patients with sepsis. Central BioHub is therefore eager to support researchers in discovering new drug targets by supplying them with human sepsis samples to conduct biomedical studies.

How can Sepsis be prevented?

The key of preventing sepsis is to avoid infections in the first place by good hygiene practices. On top of that, certain vaccinations and responsible antibiotic stewardship to avoid antibiotic resistance can help to minimize the risk of developing sepsis.

Product Page

CBH Donor ID	CBH Sample ID	Matrix	Quantity (Unit)	Age	Gender	Price	Cart
CBHD7624101	CBHS7624152	Plasma K3EDTA	0.90 (mL)	82	Female	35 €

Samples will be shipped within 5 to 10 business days.

General Data
CBH Donor ID
CBH Master ID
CBH Sample ID
Matrix Type
Matrix
Storage Container
Temperature
Storage Temperature
Freeze Thaw Cycles
Sample Condition


CBHD7624101
CBHM7624143
CBHS7624143
Plasma K3EDTA
Plasma K3EDTA
Cryotube (2 ml)
-18 °C
-18 °C
0
perfect

Quantity Information
Quantity
Unit
Total Quantity


0.90
mL
0.9

Donor
Age
Gender


82
Female

Laboratory
Lab Parameter
Result Measured In
Result Obtained From
Result Raw
Result Numerical
Result Unit
Result Interpretation
Result Date
Cut Off Raw
Cut Off Numerical
Cut Off Unit
Cut Off Remarks
Test Method
Test Kit
Test Kit Manufacturer
Test System
Test System Manufacturer


Procalcitonin (PCT)
serum
this donation
1.2
1.20
ng/mL
Positive
29.07.2021
< 0.10
0.10
ng/ml
sepsis unlikely: 0.10 - < 0.50. sepsis possible: >= 0.50 - < 2.00. sepsis likely: >= 2.00 - < 10.00. severe sepsis/septic shock most likely: >= 10.00
ECLIA (Electro Chemiluminescence Immuno Assay)
Elecsys BRAHMS Procalcitonin (PCT)
Thermo Fisher Scientific (Brahms)/Roche
Cobas 8000 (e801)
Roche

Clinical Diagnosis
Diagnosis
ICD Code
ICD Code Version
ICD Code Translation
Diagnosis Date


Acute respiratory failure, unspecified whether with hypoxia or hypercapnia	Benign essential hypertension Without mention of hypertensive urgency	Carrier of other specified bacterial diseases	Chronic kidney disease, stage 3 (moderate)	COVID-19, virus identified	Elsewhere classified, hospital-acquired pneumonia that occurs 48 hours or more after admission	Faecal incontinence	Glomerular disorders in diabetes mellitus	Hypokalemia	Isolation	Need for assistance due to reduced mobility	Need for assistance with personal care	Other specified hypothyroidism	Other viral pneumonia	Paroxysmal atrial fibrillation	Pleural effusion, not elsewhere classified	Special screening examination for infectious and parasitic diseases	Staphylococcal infection, unspecified site	Systemic Inflammatory Response Syndrome of infectious origin without organ failure	Type 2 diabetes mellitus with diabetic nephropathy	Unspecified protein-energy malnutrition
J96.00	I10.00	Z22.3	N18.3	U07.1	U69.01	R15	N08.3	E87.6	Z29.0	Z74.0	Z74.1	E03.8	J12.8	I48.0	J90	Z11	A49.0	R65.0	E11.21	E46
ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM	ICD-10-GM
Acute respiratory failure, unspecified whether with hypoxia or hypercapnia	Benign essential hypertension Without mention of hypertensive urgency	Carrier of other specified bacterial diseases	Chronic kidney disease, stage 3 (moderate)	COVID-19, virus identified	Elsewhere classified, hospital-acquired pneumonia that occurs 48 hours or more after admission	Faecal incontinence	Glomerular disorders in diabetes mellitus	Hypokalemia	Isolation	Need for assistance due to reduced mobility	Need for assistance with personal care	Other specified hypothyroidism	Other viral pneumonia	Paroxysmal atrial fibrillation	Pleural effusion, not elsewhere classified	Special screening examination for infectious and parasitic diseases	Staphylococcal infection, unspecified site	Systemic Inflammatory Response Syndrome of infectious origin without organ failure	Type 2 diabetes mellitus with diabetic nephropathy	Unspecified protein-energy malnutrition
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