Hyperthyroidism Biospecimens | Over Active Thyroid Samples

Hyperthyroidism

Hyperthyroidism is a life-long endocrine disorder resulting from over active thyroid gland producing an excess amount of T3 and T4 or both secreted into the bloodstream. It is mainly caused by autoimmune Grave's disease and other conditions like toxic multinodular goitre and toxic adenomas. It is also known as thyrotoxicosis. The exact hyperthyroidism causes are unclear. Also,hyperthyroidism are more common in women regardless of age than men in the same age group. Explore advanced search options by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

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Treatment for Graves Disease and Hyperthyroidism:

Being a chronic disorder, thyroid diseases require lifelong treatment with hyperthyroidism medications to restore and maintain normal thyroid function. Hyperthyroidism due to Graves' disease is caused by autoantibodies attacking the thyroid gland and eventually resulting in an overactive thyroid. Antithyroid medications like methimazole, radioactive iodine, and propylthiouracil are administered as the treatment for graves disease. It abstain from thyroid hormone over production and restore normal thyroid function. In some patients, surgical removal of the over active thyroid gland is warranted to prevent disease consequences.

Symptoms and Signs of Hyperthyroidism:

Over active thyroid disease is often misinterpreted as other medical conditions leading to underdiagnosis. The signs and symptoms of hyperthyroidism include excessive weight loss, increased anxiety, irritability, nervousness, trouble sleeping, scanty or irregular menses in women, goitre, heat sensitivity, blurred vision, and proximal muscle weakness. Hyperthyroidism symptoms in females significantly affect their quality of life.

Insight to the Hyperthyroidism Biospecimens We Offer:

Marking an end to the old-school procurement of research biospecimens, Central BioHub introduces you to the world's most extensive human biospecimen inventory of thyroid disease online. Leveraging novel medical research, Central BioHub delivers top-quality human biomaterials to life science researchers, pharmaceuticals, and biotech companies worldwide. Our inventory is vast; researchers can procure hard-to-find human biospecimens from our online marketplace.

Central BioHub offers  thyroid test samples ethically derived from diverse patients with hyperthyroidism. and graves We offer blood samples from thyroid patients of different ages, gender, and ethnicities. All thyroid disease biospecimens such as human serum and plasma samples are conscientiously measured for routine biochemical investigations like a thyroid-stimulating hormone (TSH) or thyrotropin, triiodothyronine (T3), thyroxine (T4), and thyroglobulin (Tg). Moreover, thyrotoxicosis samples are subjected for antibody testing like TSH receptor antibodies (TRAb), antithyroid peroxidase (aTPO / MAK) or thyroid peroxidase antibodies (anti-TPO), and anti-thyroglobulin (aTg /TAK). Our thyroid disease samples are hyper-annotated with relevant clinical information, including medical history and medication history, adding value to research. Life science researchers can purchase small and bulk volume blood samples stored at <-18°C at our partner's biobank.

 

The thyroid gland is the tiny butterfly-shaped gland located at the anterior neck. It plays a vital role in the bodys metabolic regulation by secreting triiodothyronine (T3) and thyroxine (T4)-commonly known as thyroid hormones.
Thyroid diseases can affect anyone of any age. The prevalence of the disease is more in females compared to males. Others include: • People with a family history of thyroid diseases • Patients taking certain medications like Amiodarone • Patients suffering from other autoimmune conditions like type-1 diabetes mellitus, systemic lupus erythematosus, and Sjögrens syndrome • Persons underwent past treatment for thyroid disease or cancer like thyroidectomy or radiation therapy. • People more than 60 years old, especially women
Thyroid disease requires lifelong treatment to restore and maintain thyroid function. Three is no permanent cure for thyroid diseases. Hypothyroidism caused by Hashimotos condition can be treated effectively by hormone replacement therapy with levothyroxine. On the other hand, Graves diseases hyperthyroidism requires pharmacotherapy with antithyroid medications to block excess thyroid hormone synthesis. In some cases, surgical removal of the thyroid gland and radioactive iodine treatment is required to treat hyperthyroidism.
Hyperthyroidism biospecimens comprise blood samples such as human serum and plasma collected from thyroid patients. The samples are subjected to routine thyroid function tests like a thyroid-stimulating hormone (TSH) or thyrotropin, triiodothyronine (T3), thyroxine (T4), and thyroglobulin (Tg). Additionally, serological testing for autoantibodies like TSH receptor antibodies (TRAb), antithyroid peroxidase (aTPO / MAK) or thyroid peroxidase antibodies (anti-TPO), and anti-thyroglobulin (aTg / TAK) and are also performed. The samples are cryogenically stored at <-180C at the biobank.