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endocrine disorders hypothyroidism

Hypothyroidism

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Hypothyroidism is a chronic endocrine disease resulting from an underactive thyroid gland in which the thyroid gland cannot produce and secrete enough hormones, T3 and T4.

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Hypothyroidism is mainly caused by an autoimmune condition called Hashimoto's disease. Besides, thyroidectomy, radiation therapy, and certain medications can also cause hypothyroidism and other thyroid problems. It is one of the major diseases affecting women's health worldwide. 

Hypothyroidism Symptoms and Signs:

Clinical presentation of thyroid problems is often misinterpreted as other medical conditions leading to underdiagnosis. Hypothyroidism symptoms include weight gain, thinning of hair, dry skin, cold intolerance, fatigue, frequent or heavy menstruation in women, muscle cramps, and myalgia. Moreover, hypothyroidism also causes growth and mental retardation in children.

Treatment for Hypothyroidism:

Hypothyroidism resulting from Hashimoto's disease or Hashimoto's thyroiditis is treated with thyroid hormone replacement therapy to restore normal body functions. Levothyroxine restores tissue hormone concentration and is the mainstay for thyroid hormone deficiency and related complications like myxedema coma.

Insight to the Hypothyroidism Biospecimens We Offer:

Assimilating real-world data on thyroid diseases biospecimens, our scientific customer experts at Central BioHub assist you in bringing research samples to your laboratory. We commit to the worldwide supply of safe, reliable, cost-effective biosamples for research.Central BioHub offers thyroid disease samples ethically derived from diverse patients with thyroid diseases. We bring you hypothyroidism samples from thyroid patients of different ages, gender, and ethnicities. Every human serum and plasma samples are conscientiously measured for routine biochemical investigations like a thyroid-stimulating hormone (TSH) or thyrotropin, triiodothyronine (T3), thyroxine (T4), and thyroglobulin (Tg). Moreover, Hashimoto's thyroiditis specimens are subjected for antibody testings like TSH receptor antibodies (TRAb), antithyroid peroxidase (aTPO / MAK) or thyroid peroxidase antibodies (anti-TPO), and anti-thyroglobulin (aTg /TAK).

Our thyroid test samples are hyper-annotated with clinical information, including medical history and medication history. Life science researchers can purchase small and bulk volume blood samples stored at <-18°C at our partner's biobank. All human biospecimen inventory is processed at Central BioHub in strict adherence to Helsinki's declaration and the declaration of Taipei. Contact us now for more information or for ordering hypothyroidism patient samples for your next research project.

If you're investigating autoimmune thyroid disorders, we provide Hashimoto's Thyroiditis samples for research, sourced with the highest standards. We understand the importance of pace in research, which is why we guarantee fast shipping Hypothyroidism samples, delivering what you need, when you need it.

Explore advanced search options to procure hypothyroidism biospecimens by clicking clinical diagnosis, ICD-10-CM codes, and laboratory parameters.

 

 

The thyroid gland is an essential endocrine gland that plays a crucial role in body metabolism, growth and development. It synthesis and secrete thyroid hormones into the bloodstream, namely, triiodothyronine (T3) and thyroxine (T4)
It is a chronic endocrine disorder in which the thyroid gland cannot produce and release enough T3 and T4 hormones in hypothyroidism due to an underactive thyroid gland. It is primarily caused by Hashimotos disease, an autoimmune condition
Anyone can develop thyroid disease at any age. Females are more likely to develop the condition than males. The following are the risk factors for thyroid disorders. Patients with a family history of thyroid disease • Patients who take certain medications, such as Amiodarone • Patients with other autoimmune conditions, such as type-1 diabetes mellitus, systemic lupus erythematosus, and Sjogren syndrome • Individuals who have undergone thyroid surgery or radiation therapy in the past. The elderly, especially women over the age of 60.
Long-term untreated hypothyroidism can lead to several health complications like goiter, Infertility. Cardiovascular problems, mental health problems, Peripheral neuropathy. Myxedema, congenital disabilities.