Hypothyroidism is primarily caused by an autoimmune condition called Hashimoto's disease. Other causes include thyroidectomy, radiation therapy, and certain medications. It is a significant health concern for women worldwide.
Symptoms and Signs of Hypothyroidism
The clinical presentation of hypothyroidism is often misinterpreted as other medical conditions, leading to underdiagnosis. Symptoms include:
In children, hypothyroidism can cause growth and mental retardation.
Treatment for Hypothyroidism
Hypothyroidism resulting from Hashimoto's disease is treated with thyroid hormone replacement therapy to restore normal body functions. Levothyroxine is the main treatment, restoring tissue hormone concentration and addressing related complications such as myxedema coma.
Hypothyroidism Biospecimens from Central BioHub
At Central BioHub, we offer a comprehensive collection of hypothyroidism biospecimens for research, ethically derived from diverse patients of various ages, genders, and ethnicities. Our biospecimens include human serum and plasma samples measured for routine biochemical investigations like:
Hashimoto's thyroiditis specimens are subjected to antibody testing, including:
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TSH receptor antibodies (TRAb)
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Antithyroid peroxidase (aTPO/MAK)
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Anti-thyroglobulin (aTg/TAK)
Our thyroid test samples are hyper-annotated with clinical information, including medical and medication history. Researchers can purchase small and bulk volume blood samples stored at <-18°C from our partner's biobank. All human biospecimen inventory is processed at Central BioHub in strict adherence to the Declaration of Helsinki and the Declaration of Taipei.
Contact us now for more information or to order hypothyroidism patient samples for your next research project. For those investigating autoimmune thyroid disorders, we provide Hashimoto's Thyroiditis samples sourced with the highest standards. We understand the importance of speed in research and guarantee fast shipping, delivering what you need, when you need it.
Explore advanced search options to procure hypothyroidism biospecimens by clicking Clinical Diagnosis, ICD-10-CM codes, Matrix, and Laboratory Parameters.