Hepatitis

Hepatitis refers to the acute or chronic liver disease caused by viral infection. In humans, it is caused by five clinically significant hepatotropic viruses attacking the liver cells, namely, hepatitis A virus (HAV), hepatitis B (HBV), hepatitis D virus (HDV), hepatitis C (HCV), hepatitis E virus (HEV), and hepatitis G virus (HGV). It can affect anyone of any age group causing acute hepatitis or chronic liver inflammation. It is one of the major liver infections that can be fatal or cause liver cirrhosis, hepatocellular carcinoma, liver failure, etc. Explore advanced search options by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

Show rows
|< < of > >|

Viral Hepatitis can affect anyone of any age group causing acute or chronic liver infection. HAV and HEV infections are usually acute self-limiting liver disease with a low fatality rate transmitted through the orofecal route by consuming contaminated food and water and confers lifelong immunity. On the other hand, hepatitis B and C infection cause chronic liver infection, leading to life-threatening consequences, even death due to liver cirrhosis, hepatocellular carcinoma, liver failure, or unrelated medical conditions. Furthermore, HDV and HGV are satellite viruses propagating as co-infections with Hepatitis B and C infection. Therefore, Hepatitis B and C are blood-borne infections caused by blood and blood product exposure predominantly during blood transfusion, haemodialysis, and parenteral drug use.  Besides, sexual intercourse and perinatal transmission are also observed.


Hepatitis Symptoms and Signs:

Hepatitis viruses are sneaky viruses, with slow progression of illness-causing inflammation and scarring of the liver tissues, eventually causing liver diseases such as cirrhosis or liver carcinoma. The infected person remains asymptomatic for several years while the liver damage occurs silently. Generally, the illness begins with flu-like symptoms like headache, low-grade fever, myalgia, fatigue, and generalized malaise. In later stages, the patient also experiences liver disease symptoms of jaundice, lack of appetite, abdominal pain, nausea, weight loss, dark coloured urine, dry and itchy skin.


Insight to Hepatitis Biospecimens We Offer:

Driven by technological advancement, Central BioHub designed an ultimate solution for your biospecimen needs. With the experience and expertise in serving renowned clinical research organizations, pharmaceuticals, biotech companies, governmental and academic research organizations worldwide, we escalate our service by providing superior quality human specimens for research through our online marketplace.
Accelerating universal research on hepatitis, we bring you millions of defined, well-annotated human specimens critically isolated from consented patients with hepatitis. Our modernized extensive biorepository stores research biofluids ranging from small to bulk volumes with perfect storage conditions to best meet your research endpoints.

 

Hepatitis research samples we provide include:

Hepatitis A virus (HAV) Infection samples: It comprises human biospecimens containing positive molecular results for HAV infection intended for viral hepatitis research purposes. Serum and plasma samples are explicitly tested for specific antibodies such as HAV IgM antibody, HAV IgG antibody, and hyper annotated with relevant clinical information, stored at<-18 degree Celsius at our biobank.
 

  • Hepatitis B virus (HBV) Infection samples: It comprises genetically diverse serum and plasma samples ethically obtained from patients and precisely measured for hepatitis B core antibody (anti-HBc), Hepatitis B surface antibody (anti-HBs), Hepatitis B surface antigen (HBsAg), and HBV DNA quantitative viral load intended for research purpose.
  • Hepatitis C virus (HCV) Infection samples: It contains hepatitis research samples such as human serum and plasma samples tested for HCV antibody (anti-HCV), HCV antigen (HCV Ag), HCV RNA, HCV Genotype, HCV quantitative viral load and stored at <-18°C at our partner's biobank.
  • Hepatitis D virus (HDV) Infection Samples: It comprises serum and plasma samples collected from patients suffering from hepatitis D virus infection tested for hepatitis delta virus antibody (anti-HDV) intended for in-vitro research (IVD) purposes.
  • Hepatitis E virus (HEV) Infection samples: It comprises high-quality biofluids such as serum and plasma samples with positive molecular results of hepatitis E virus (HEV). The blood samples are screened for Hepatitis E virus antibody (anti-HEV) for disease confirmation and stored at <-18°C at our biorepository.
  • Hepatitis G virus (HGV) Infection samples: It contains blood-derived biosamples collected from hepatitis patients appropriately tested for Hepatitis G virus antibody (anti-HGV) through polymerase chain reaction (PCR).

 

Central BioHub delivers you biosamples for acute hepatitis or chronic hepatitis  that are immediately available, ethically obtained, cautiously preserved,  and precisely handled to optimize diagnostic yield and enhance life science discovery. Our experts at Central BioHub assist you in every step of biospecimen procurement. Contact us for more information on the research sample . We are curious to hear from you.

Viral hepatitis refers to acute and chronic liver infection causing liver inflammation and hepatocellular damage. It is caused by a group of hepatotropic viruses, namely, hepatitis A virus (HAV), hepatitis B (HBV), hepatitis D virus (HDV), hepatitis C (HCV), hepatitis E virus (HEV), and hepatitis G virus (HGV).
Hepatitis A, hepatitis B, hepatitis C are the viral liver infections caused by hepatitis A virus, hepatitis B virus, and Hepatitis C virus. • Hepatitis A infection is usually a self-limiting acute viral infection manifested by mild to moderate symptoms. It is generally associated with a low fatality rate and confers life-long immunity against the respective viral pathogens. • Hepatitis B and hepatitis C infections show similar symptoms and exist in two forms; acute and chronic diseases. However, hepatitis C infection tends to be more chronic. Hepatitis B virus transmits mainly through body fluids, and hepatitis C is transmitted through blood and blood products. If not treated adequately at the right time, both infections can result in life-threatening conditions like liver failure, liver cirrhosis, and liver carcinoma. Currently, preventive vaccinations are available for hepatitis A and B infection; however, there are no vaccines available for hepatitis C, and medication must be started in the first year after infection to allow for a complete recovery.
Viral hepatitis can be diagnosed effectively by the following: • Physical examination • Blood test for assessing liver functions • Radio diagnoses such as ultrasound, CT, MRI, and transient elastography for assessing liver tissue damage and disease progression • Liver biopsy
Every hepatitis is treatable. Hepatitis A infection is usually self-limiting with extremely low fatality rates and requires only supportive care. On the other hand, hepatitis B and C infection can be treated with medications to control the virus, delay disease progression, and prevent liver damage.