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West Nile Virus

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West Nile disease, also commonly known as West Nile fever, is a mosquito-borne tropical infection caused by the West Nile virus (WNV), an RNA virus belonging to the family Flavivirus. The Zoonotic disease is endemic in the continental United States and Europe, primarily transmitted to humans by the bite of the infected Culex mosquitoes.

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While the majority of West Nile fever cases are asymptomatic or with mild symptoms, some patients face a severe course of disease. Central BioHub offers researchers worldwide West Nile Virus samples of infected donors to enlighten the physiology behind this disease. 

Birds are the primary host of the West Nile virus (WNV), and upon feeding, the virus infects mosquito-vectors, subsequently infecting humans by infected Culex mosquito bites. Therefore, the WNV life cycle often alternates between host birds and mosquito-vectors. However, the transmission of infection is also reported from human to human through laboratory acquisition, blood transfusion, organ transplantation, breastfeeding, and transplacental transmission and is often rare.

The major contributing factor for the widespread disease is replicating mosquito-vectors transmitting the virus in favorable seasons. Therefore, public health initiatives for effective mosquito control and personal protection against mosquito bites are the best way to prevent virus invasion.

West Nile symptoms:

Most individuals infected with the West Nile virus are asymptomatic or exhibit mild symptoms and are self-limiting. However, the symptomatic patients exhibit a sudden onset of headache, malaise, low-grade fever, myalgia, chills, vomiting, fatigue, and rashes. In severe viraemia cases, the infection can prolong and develop into neuroinvasive diseases manifested by encephalitis, meningitis, or acute flaccid paralysis. Besides, Lack of FDA-approved vaccination and definitive antiviral therapy can increase the risk of infection-associated fatalities. Therefore, timely differential diagnosis and early initiation of supportive therapy with close monitoring can reduce the complications.

Diagnosis of West nile Virus:

For preliminary diagnosis of West Nile disease, physical examination, endemic area exposure, and patient history are helpful. Confirmatory diagnosis usually rests on serological testing and cerebrospinal fluid (CSF) analysis to detect anti-WNV IgM antibodies by molecular diagnostic tests like ELISA and RT-PCR.

Insight to the West Nile Fever Samples We Offer:

Central BioHub is an ideal pathway to procure trusted human biomaterials through a hundred percent reliable innovative virtual platform. We provide biospecimens derived from suspected and clinically confirmed patients of every age, gender, and ethnicity complying with the mandatory standard declarations ideal for tropical research.

The West Nile virus biospecimens are isolated and stored in the most hygienic laboratory environment operated at optimum conditions to make the samples devoid of contaminations. Central BioHub offers West Nile test samples such as saliva, blood, urine, plasma, and serum samples that are tested for West Nile virus IgG and IgM. 

A new outlook to scientific advancements and biomedical and diagnostic research is the long-term goal of Central BioHub, and we strive to contribute the best of our services towards the betterment of science and  clinical research on tropical disease and neglected tropical diseases. The group of devoted scientific experts of Central BioHub is our epitome, guaranteeing every West Nile disease biospecimen with perfection and utmost reliability. Customer satisfaction and quality service are our priorities. Reach out to us to procure the most authentic, high-quality, and cost-effective tropical disease samples collected exclusively for Tropical medicine and infectious disease research.

Explore advanced search options to procure West Nile Virus biospecimens and other tropical disease biospecimens by clicking clinical diagnosis, ICD-10-CM codes, and laboratory parameters.

West Nile virus (WNV) is an RNA virus known to cause West Nile fever in humans. It is transmitted by the bite of infected Culex mosquitoes and characterised by abrupt onset of headache, malaise, low-grade fever, myalgia, chills, vomiting, fatigue, and rashes.
The people who reside in the West Nile virus endemic regions are more prone to the illness. However, elderly persons and people with other chronic underlying diseases such as diabetes mellitus, cancer, hypertension, kidney disease, etc are at greater risk of developing severe disease.
Despite the lack of approved specific vaccination, West Nile virus infection is effectively prevented by the following measure: - Avoid travelling to West Nile fever endemic areas. - Use mosquito repellents to prevent mosquito bites. - Wear long-sleeved shirts and pants to avoid mosquito bites. - Use air conditioning, door, and window screen to prevent mosquito entry indoors. - Sleep under mosquito nets - Eat nutritious diet - Stay hydrated by drinking plenty of fluids - Avoid stagnant water where mosquitoes can breed
West Nile infection samples are human biospecimens such as saliva, urine, whole blood, serum, and plasma derived from persons suspected or clinically confirmed with West Nile virus infection. The human biofluids are tested for West Nile virus antibodies IgM and are preserved cryogenically at our biobank.