Food Allergens

Q: What is a food allergy?

In the case of a food allergy, the immune system of the affected person reacts to normally harmless foods with an excessive defensive reaction. The body forms defensive antibodies, mostly IgE, against certain protein components called allergens. Why the immune system in some people reacts exaggeratedly to certain food components has not yet been precisely clarified. In addition to environmental factors, hereditary probably also play a role here.

Q: What are the symptoms of food allergies?

In IgE-mediated food allergies, allergic symptoms usually occur within a few minutes to two hours. The location of the reaction and how strongly they occur varies from person to person. Reactions often take place on the mucous membranes, for example in the form of inflammation of the intestinal mucosa, watery and swollen eyes, runny nose, sneezing, coughing, or asthma attacks with shortness of breath. In addition, skin rashes, eczema, wheal formation, and itching as well as diarrhea, nausea, or flatulence often occur with a food allergy.

Q: What kind of food allergies exist?

The prevalence of food allergies is reported to range from 1 to 10% of the total population and depends on multiple factors. The dietary behavior in various countries plays a decisive role. Certain types of food trigger these allergies more often than others. These include nuts, wheat, milk, seafood, soy, and chicken eggs.

Q: How to recognize and treat food allergies?

A blood test indicates whether the body has produced specific antibodies, predominantly IgE antibodies. In a skin test, a solution containing food protein is applied to the lightly scratched skin and observed to see whether it turns red or itchy wheals appear. If an allergy is detected, the most important treatment is to avoid the triggering food. In case of severe allergies, an emergency kit with epinephrine injection, antihistamine, and cortisone tablets is necessary, which can be applied in case of anaphylactic reactions.

Q: What are food allergy samples?

Central BioHub provides thousands of serum samples isolated from consented donors and indicated for in-vitro biomedical research. The biospecimens are tested for sIgE for different food allergens and stored at <-18 °C at our biobank. Positive tests are arranged into four groups, the so-called RAST classes, of which class 1 represents the lowest and class 4 the highest content of specific IgE.

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Food Allergy is one of the most common allergies that affect men and women regardless of age. It is the condition in which the immune system overreacts to some food substances or their ingredients, triggering the production of antibodies to eliminate the threat.

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Allergies can be inherited or acquired, and individuals may develop an allergy to a particular food to which they have not been allergic in the past. Common food allergies include shellfish allergy, dairy allergy, fruit allergy, and many others. Correct diagnosis and complete avoidance of the allergic substance are key to preventing severe reactions like anaphylaxis.

Signs and Symptoms of Food Allergy

Typically, upon ingesting the allergic food, the symptoms and signs begin to manifest. However, the severity of the symptoms varies from person to person depending upon their immune response. Common symptoms include:

Mouth itching
Hives
Difficulty swallowing
Breathlessness
Abdominal pain
Nausea and vomiting
Dizziness
Diarrhea
Itchy and watery eyes
Angioedema
Hay fever

In severe cases, some individuals develop anaphylaxis, characterized by sudden onset of respiratory distress, chest congestion, swollen tongue, and even coma. Prompt medical attention is crucial in such scenarios to prevent fatal outcomes.

Insight into Food Allergy Samples/Food Allergy Panels We Offer

Trusted by millions of researchers worldwide, Central BioHub continues to be the world's most trusted marketplace for allergy patient samples. We have a proven history of collaborations with renowned pharmaceutical, biotech, governmental, and academic biomedical research institutions globally.

We offer food allergens tested samples such as human serum and plasma samples collected from patients diagnosed with food allergies. Specific IgE tests are performed to identify the exact allergens, and the samples are stored cryogenically at <-18°C at our partner's biobank. Additionally, we offer samples from patients undergoing food allergy treatment. All our food allergy samples are well-annotated with detailed clinical information, including the donor's age, sex, ethnicity, and are directly available for purchase. Contact our customer management team for further queries and secure your food allergy biospecimens and other allergy specimens today!

Applications of Food Allergy Samples in Research

Food allergy samples are invaluable in various research fields. Here are some key applications:

Immunology Research: Understanding the immune response mechanisms to allergens helps in developing new treatments and vaccines.
Genetic Studies: Researching genetic predispositions to food allergies can lead to personalized treatment strategies and preventive measures.
Diagnostic Development: Creating more accurate and faster diagnostic tools to identify food allergies.
Therapeutic Research: Developing novel therapies, including immunotherapies and desensitization protocols, to manage and treat food allergies.
Public Health Studies: Assessing the prevalence and impact of food allergies in different populations helps in formulating public health policies and awareness programs.
Nutritional Research: Studying the nutritional deficiencies and dietary adjustments required for individuals with food allergies.

Current Research and Innovations with Food Allergy Samples

Recent advancements in technology have significantly enhanced the scope of food allergy research. Some of the exciting areas of current research include:

Molecular Allergen Profiling: Advanced techniques are being used to profile specific allergens at the molecular level, providing insights into their structure and potential cross-reactivity with other allergens.
Biomarker Discovery: Identifying biomarkers that can predict the severity of allergic reactions and the effectiveness of treatments.
Epigenetic Studies: Investigating how environmental factors and lifestyle choices influence the development and severity of food allergies through epigenetic modifications.
Probiotic and Microbiome Research: Exploring the role of gut microbiota in the development and management of food allergies, and how probiotics can modulate immune responses.
Novel Immunotherapies: Developing new forms of immunotherapy that can desensitize patients to specific food allergens, reducing the risk of severe reactions.
Allergen-Specific IgE and IgG Testing: Improving the specificity and sensitivity of tests to measure allergen-specific antibodies, aiding in accurate diagnosis and monitoring of food allergies.
Artificial Intelligence and Machine Learning: Utilizing AI and machine learning algorithms to predict allergy outcomes, personalize treatments, and analyze large datasets for better understanding of food allergies.

The use of food allergy samples in biomedical research is unlocking new possibilities in understanding and treating food allergies. From immunology and genetic research to the development of novel diagnostics and therapeutics, these samples are integral to advancing scientific knowledge and medical innovation. Central BioHub offers a vast collection of high-quality food allergy samples, providing researchers with the resources they need to drive their studies forward. Explore our inventory online, reserve samples, or create a quote today. For more information or assistance, contact Central BioHub.

Feel free to reach out to Central BioHub for further details or to explore our inventory of high-quality food allergy samples for your research needs.

Explore advanced search options to discover food allergy biospecimens by clicking Clinical Diagnosis, ICD-10-CM codes, Matrix, and Laboratory Parameters.

What is a food allergy?

In the case of a food allergy, the immune system of the affected person reacts to normally harmless foods with an excessive defensive reaction. The body forms defensive antibodies, mostly IgE, against certain protein components called allergens. Why the immune system in some people reacts exaggeratedly to certain food components has not yet been precisely clarified. In addition to environmental factors, hereditary probably also play a role here.

What are the symptoms of food allergies?

In IgE-mediated food allergies, allergic symptoms usually occur within a few minutes to two hours. The location of the reaction and how strongly they occur varies from person to person. Reactions often take place on the mucous membranes, for example in the form of inflammation of the intestinal mucosa, watery and swollen eyes, runny nose, sneezing, coughing, or asthma attacks with shortness of breath. In addition, skin rashes, eczema, wheal formation, and itching as well as diarrhea, nausea, or flatulence often occur with a food allergy.

What kind of food allergies exist?

The prevalence of food allergies is reported to range from 1 to 10% of the total population and depends on multiple factors. The dietary behavior in various countries plays a decisive role. Certain types of food trigger these allergies more often than others. These include nuts, wheat, milk, seafood, soy, and chicken eggs.

How to recognize and treat food allergies?

A blood test indicates whether the body has produced specific antibodies, predominantly IgE antibodies. In a skin test, a solution containing food protein is applied to the lightly scratched skin and observed to see whether it turns red or itchy wheals appear. If an allergy is detected, the most important treatment is to avoid the triggering food. In case of severe allergies, an emergency kit with epinephrine injection, antihistamine, and cortisone tablets is necessary, which can be applied in case of anaphylactic reactions.

What are food allergy samples?

Central BioHub provides thousands of serum samples isolated from consented donors and indicated for in-vitro biomedical research. The biospecimens are tested for sIgE for different food allergens and stored at <-18 °C at our biobank. Positive tests are arranged into four groups, the so-called RAST classes, of which class 1 represents the lowest and class 4 the highest content of specific IgE.