Inflammatory Bowel Disease | Human Biospecimens Online

Inflammatory Bowel Disease

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Inflammatory bowel disease (IBD) is a chronic autoimmune disorder characterized by progressive inflammation of the gastrointestinal tract (GIT), resulting in GI damage. It comprises two inflammatory conditions: Crohn's disease and ulcerative colitis.

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IBD results from a faulty immune response to the environmental triggers causing colon inflammation. However, the exact etiology of IBD is still unknown. It is one of the common chronic conditions affecting the adult population globally. Therefore, the growing prevalence of the illness boosted more clinical research opportunities worldwide. 

Crohn’s disease (CD) is the transmural inflammation of gastrointestinal mucosa occurring at any part of GIT from mouth to anus.

  • Ulcerative colitis (UC) is the mucosal or submucosal inflammation confined to the rectum and colon. Chronic ulcerative colitis increases the risk of colorectal cancers.

Inflammatory Bowel Disease Signs and Symptoms:

Crohn’s disease and ulcerative colitis common signs and symptoms include persistent diarrhea or frequent bowel movements, fatigue, abdominal pain or cramps, weight loss, rectal bleeding, reduced appetite, bloody stools, and arthritis. However, early diagnosis and timely initiation of treatment can improve the quality of life of affected ones.


Treatment of Inflammatory Bowel Disease:

There is no permanent cure for inflammatory bowel disease. However, the present treatment aims at symptomatic relief, prolonged remission and preventing complications. For reducing the GUT inflammation, glucocorticosteroids and aminosalicylates such as Mesalamine, Balsalazide, and Sulfasalazine are administered as first-line therapy. Furthermore, immunosuppressants, biological agents, and antibiotics are used as adjuvant therapy based on disease progression.


An insight into Inflammatory Bowel Disease Samples we offer:

Central BioHub is the global online market leader for research biospecimens acquisition. We leverage the global supply of genuine human biospecimens from certified biorepositories to your laboratory. Our specialized inventory, expertise, and global clinical network cater to your biospecimens needs.

Being the largest global provider of Ulcerative colitis samples and Crohn's disease specimens, Central BioHub brings you a wide array of human human serum and plasma samples obtained from patients suffering from inflammatory bowel disease (IBD), specifically Crohn’s disease and ulcerative colitis. Studies on IBD samples helps to explore more about the disease and help the researchers trying to develop new treatments.The inflammatory bowel disease samples comprise of human serum, plasma and whole blood samples that are conscientiously tested in certified laboratories for mandatory autoimmune parameters such as capsule-reactive protein (CRP), complement C3, complement C4, anti-saccharomyces cerevisiae antibodies (asCa). Besides, biomarkers like bone-specific alkaline phosphatase (BAP, anti-double-stranded DNA (dsDNA), anti-neutrophil cytoplasmic antibodies (ANCA), antinuclear antibodies (ANA) and rheumatoid factors (RF) are also tested. Substantiating research specificity and accuracy, our Inflammatory bowel disease biospecimens are hyper-annotated with relevant clinical information, medication history, and patient demographics like age, gender, race, ethnicity, and country of sample origin. Moreover, our biorepository stores the blood samples at <-18 degree Celsius and readily available for purchase in small volumes. Hurry up, order IBD patient specimens for research at Central BioHub. Contact us now for more information on autoimmune disease samples.

Explore advanced search options to order Inflammatory Bowel Disease Samples by clicking Clinical Diagnosis, ICD-10-CM codes, Matrix, and Laboratory Parameters.

 

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IBD is a chronic autoimmune disorder characterised by prolonged inflammation of the gastrointestinal tract. It comprises two conditions: ulcerative colitis and Crohn’s disease.
Specific complications of ulcerative colitis and Crohns disease differ from each other. However, common complications of IBD are colon cancer, arthritis, uveitis-eye and skin inflammation, and primary sclerosing cholangitis.
Exact reason for IBD is still unknown. However, the following risk factors are identified for developing the illness: • Genetic factors: people having a family history of IBD • Autoimmunity • Cigarette smoking • Ethnicity- whites have a greater risk of developing the illness • Increasing age • Medications like nonsteroidal anti-inflammatory drugs
Inflammatory bowel disease biospecimens are human serum and plasma samples collected from patients suffering from IBD, such as ulcerative colitis and Crohn’s disease, ideal for biomedical research.
Besides the physical examination, patient history, and clinical presentation, prompt and accurate diagnosis of IBD is made through: • Blood tests- examines inflammation biomarkers like C-reactive proteins and ESR. • Stool testing for faecal biomarkers like faecal calprotectin and faecal lactoferrin. • Endoscopic procedures- uses a combination of endoscopy, biopsy, and colonoscopy. • Radio imaging procedure- X-ray, CT scan, and MRI