Type 1 Diabetes Biospecimens for Research| Order Online

Diabetes I

Type 1 diabetes mellitus is also known as insulin dependent diabetes mellitus (IDDM), affects sugar metabolism. It mainly develops due to autoimmune-mediated destruction of pancreatic beta cells with the production of autoantibodies like islet cell antibodies and insulin antibodies against beta-cell antigens by macrophages and T-lymphocytes. Although illness onset can be at any age, Type 1 diabetes mellitus strikes children and young adults the most. Therefore, it is also known as juvenile diabetes. Moreover, the present decade is witnessing a hike in the incidence of type 1 diabetes, influencing the health-related quality of life of the young generation. Explore advanced search options to order type 1 diabetes samples by clicking CLINICAL DIAGNOSIS, ICD-10-CM CODES, and LABORATORY PARAMETERS.

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Signs and Symptoms of Type 1 Diabetes Mellitus:

Juvenile diabetes symptoms often shows a sudden  and is similar as type 2 diabetes symptoms that includes:

  • Polyphagia (extreme hunger)
  • Polydipsia (increased thirst)
  • Polyuria (frequent urination, sometimes unusual bedwetting in children)
  • Sudden unintended weight loss
  • Lethargy and weakness
  • Hyperglycemia-increase in blood sugar level
  • Irritability and mood swings
  • Blurred vision

 

Type 1 diabetes treatment modalities:

A permanent cure for type 1 diabetes mellitus is not possible. However, type 1 diabetes treatment options mainly focus on controlling blood sugar levels, preventing complications, reducing mortality, and improving the patient's quality of life. Therefore, lifelong therapy with insulin analogues is required for treating illness. Depending upon the blood sugar level, dosage fixation, and choice of insulin such as short-acting (regular), rapid-acting, intermediate-acting, and long-acting insulin are decided. Often insulin is administered subcutaneously and, if necessary, intravenously to maintain normal blood glucose levels. Besides, strict adherence to the diet plan and regular exercise is crucial for achieving antidiabetic treatment’s goal.


An insight into Type 1 Diabetes Biospecimens we offer:

Helping diabetic researchers across the globe, Central BioHub provides trustworthy premium quality, clinically graded type 1 diabetes patient samples for research. The clinical research samples include human serum and plasma (K3 EDTA, K2 EDTA, EDTA, Li-heparin plasma samples obtained from various consented donors, clinically suspected or confirmed with type 1 diabetes mellitus. Moreover, the diabetes samples we provide are hyper-annotated with patients' medical information, including medication history and demographic data such as age, gender, ethnicity, and country of sample origin.

 

Adhering to the customised standard procedures for sample collection and processing, the serum and plasma samples are tested for routine laboratory investigation parameters for diagnosing type 1 diabetes. The diabetes samples we offer are critically screened for diabetic biomarkers, like islet cell cytoplasmic autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA) at certified, world-class laboratories, and well maintained at <-18 °C at our biorepository. Procure your clinical research sample today from Central BioHub, the largest online biospecimens marketplace. Reach out to us for finding Diabetes specimens and other  human biospecimens  for clinical research.

Type 1 diabetes mellitus, also known as insulin-dependent diabetes mellitus (IDDM), is a metabolic disorder characterised by increased blood glucose levels. It is caused when the bodys immune system destroys pancreatic beta cells by autoimmunity. Pancreatic beta cells are responsible for producing insulin to regulate blood glucose. Therefore, its destruction results in an imbalance between insulin demand and production, eventually causing hyperglycemia. Although illness onset can be at any age, children and young adults are majorly struck with type 1 diabetes mellitus. Therefore, it is known as juvenile diabetes.
Children and young adults with a family history, such as having a parent or siblings with type 1 diabetes mellitus, are at high risk of developing the illness.
Type 1 Diabetes mellitus is an autoimmune disorder resulting from immune-mediated destruction of pancreatic beta cells. In comparison, type 2 Diabetes mellitus develops due to insulin resistance or insufficient insulin production. Furthermore, type 1 diabetes mellitus is diagnosed in children and young adults; on the other hand, type 2 diabetes mellitus is an adult onset disease.
Type 1 diabetes mellitus biospecimens include human serum and plasma samples derived from clinically confirmed patients and suspected individuals. The biosamples are subjected to diabetic biomarker testing, such as autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA), and are stored at <-180 C.
Type 1 diabetes mellitus is diagnosed by routine diabetes investigations, such as fasting blood sugar (FBS), random blood sugar (RBS), and postprandial blood sugar (PPBS). Additionally, diabetic biomarker tests like autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA) yield specific confirmation of the disease.