Type I Diabetes Samples | Human Biospecimen Samples

Type I Diabetes Samples

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Type I diabetes samples are crucial for researchers working to understand and combat Type 1 diabetes mellitus, also known as insulin-dependent diabetes mellitus (IDDM). This chronic condition affects sugar metabolism and primarily arises from an autoimmune-mediated destruction of pancreatic beta cells.

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Although Type I diabetes can develop at any age, it predominantly strikes children and young adults, which is why it is also referred to as juvenile diabetes. The incidence of Type 1 diabetes is increasing, presenting a significant challenge to the health-related quality of life for the younger population.

Signs and Symptoms of Type 1 Diabetes Mellitus

The symptoms of juvenile diabetes often appear suddenly and can be quite similar to those of Type 2 diabetes. The most common signs and symptoms include:

  • Polyphagia (extreme hunger)
  • Polydipsia (increased thirst)
  • Polyuria (frequent urination, sometimes resulting in unusual bedwetting in children)
  • Sudden unintended weight loss
  • Lethargy and weakness
  • Hyperglycemia (increased blood sugar level)
  • Irritability and mood swings
  • Blurred vision

Type 1 Diabetes Treatment Modalities

Currently, there is no permanent cure for Type 1 diabetes mellitus. Treatment primarily focuses on managing blood sugar levels, preventing complications, reducing mortality, and improving the patient’s quality of life. Lifelong therapy with insulin analogues is essential for managing the disease. Depending on the blood sugar levels, healthcare providers determine the appropriate dosage and type of insulin, which may include short-acting (regular), rapid-acting, intermediate-acting, and long-acting insulin. Insulin is usually administered subcutaneously and, when necessary, intravenously, to maintain normal blood glucose levels. Alongside insulin therapy, strict adherence to a diet plan and regular exercise are critical components of an effective antidiabetic treatment regimen.

An Insight into Type 1 Diabetes Biospecimens We Offer

Central BioHub is dedicated to supporting diabetes research globally by providing premium-quality, clinically graded Type 1 diabetes samples for research. Our collection includes human serum and plasma samples (K3 EDTA, K2 EDTA, EDTA, Li-heparin) obtained from consented donors who are either clinically suspected or confirmed to have Type 1 diabetes mellitus. Each sample is hyper-annotated with detailed medical information, including medication history, and demographic data such as age, gender, ethnicity, and country of sample origin.

We adhere to stringent standard procedures for sample collection and processing to ensure the reliability and integrity of our biospecimens. The serum and plasma samples are thoroughly tested for routine laboratory parameters used in diagnosing Type 1 diabetes. Additionally, our Type 1 diabetes samples are critically screened for diabetic biomarkers, including islet cell cytoplasmic autoantibodies (ICA), insulin autoantibodies (IAA), and glutamic acid decarboxylase autoantibodies (GADA). All testing is conducted in certified, world-class laboratories, and the samples are preserved at temperatures below -18 °C in our biorepository.

Procure Your Type 1 Diabetes Samples Today

At Central BioHub, we make it easy for researchers to access the Type 1 diabetes samples they need for their studies. As the world’s largest online biospecimens marketplace, we offer a vast collection of high-quality, well-characterized samples that can significantly advance diabetes research. Whether you are studying the pathophysiology of Type 1 diabetes, testing new treatments, or exploring diagnostic biomarkers, our samples provide a solid foundation for your work.

Explore advanced search options to order type 1 diabetes samples by clicking Clinical Diagnosis, ICD-10-CM codes, Matrix, and Laboratory Parameters.

Type 1 diabetes mellitus, or insulin-dependent diabetes mellitus (IDDM), is a metabolic disorder characterized by an increase in blood glucose levels. Autoimmune destruction of pancreatic beta cells by the immune system causes it. Pancreatic beta cells are responsible for producing insulin to regulate blood glucose. Therefore, its destruction results in an imbalance between insulin demand and production, eventually causing hyperglycemia. Although illness onset can be at any age, children and young adults are disproportionately affected by type 1 diabetes mellitus. This is why it is called juvenile diabetes.
The incidence of type 1 diabetes mellitus is higher in children and young adults who have a family history of the disease.
Type 1 Diabetes mellitus is an autoimmune disorder resulting from immune-mediated destruction of pancreatic beta cells. In comparison, insulin resistance or inadequate insulin production causes type 2 diabetes mellitus. The onset of type 1 diabetes mellitus occurs most often in children and young adults; the onset of type 2 diabetes mellitus occurs most often in adults.
Type 1 diabetes mellitus samples are serum and plasma samples collected from clinically confirmed patients and suspected individuals indented for research use. All the samples are subjected to diabetic biomarker testing, such as autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA), and are stored at <-180 C.
Blood sugar testing is the mainstay for the disgnosis of type 1 diabetes mellitus. It includes fasting blood sugar (FBS), random blood sugar (RBS), and postprandial blood sugar (PPBS). Additionally, diabetic biomarker tests like autoantibodies (ICA), insulin autoantibodies (IAA), glutamic acid decarboxylase autoantibodies (GADA) yield specific confirmation of the disease.